Klaue ricerca

Fields of basic and clinical research

–  Development of a computerized 3-D imaging system using personal computers to be used for diagnostic purposes in Orthopaedics and pre-operative simulation of corrective means.

–  Development of a Universal Internal Fixation Plate

–  Bone formation and regeneration

–  Development of prosthetic fixation with remodeling interface

–  Development of improved in Foot and Ankle Reconstruction techniques

–  Development of Osteosynthetic Fixation Plates and Screws

–  Development of specific implants and instruments to be used in Foot and Ankle surgery

Nail for internal fixation of the hindfoot (tibio-calcaneal arthrodesis). It is essential to fix the hindfoot in anatomical alignment and under stable conditions to achieve secure bone healing. The bones of the hindfoot are aligned on a circular arc.



First or only author, all swiss (priority (pri) and US applications (US-publication dates listed (pub).

(pri = priority CH (first application))
(pub = published USA)

1.  Self compressing plates with variable slope
pri: 16.03.81, pub: 30.04.85

2.  The Dynamic Compression Unit (DCU)
pri: 20.11.80, pub: 15.01.85

3.  Universal drill guide for compression plates (DCU)
pri: 29.11.81, pub: 15.07.86

4.  Self locking (self interlocking) medullary nail
pri: 14.05.84, pub: 10.11.87

5.  Osteosynthetic plate with trapezoidal cross section
pri: 30.08.85, pub: 13.06.89

6.  LC-DCP (low contact compression plate)
pri: 2.12.87, pub: 26.03.91

7.  Self locking shaft prosthesis for hemi- or total arthroplasties
pri: 05.07.89, USA: examination going on, PCT(world) pub: 25.01.90

8.  Shaft prosthesis fixation with variable interface (continuous adaptation to endosteal remodelling of bone)
pri: 07.12.89, USA: pending, PCT(world) pub: 27.06.91

9.  Strain washer for plate osteosynthesis (further development of the LC-DCP (6))
pri: 25.01.93, pub. (Euro. Pat.) 27.05.98, PCT(world) pub: 04.08.94

10.  Lock washer for bone plate osteosynthesis
USA pub: 27.05.97

11.  Osteosynthetic Bone plate and lock washer
USA pub: 12.02.97

12.  Symmetrical Bone Plate (further development of (6) and (9))
pri: 04.09.97, PCT (world) pub: 11.03.99, USA 05.12. 2001

13.  Vorrichtung zur temporären Schienung von Zehen
pri: 10.04.2003, PCT (world) pending

14.  Vorrichtung zur temporären Schienung von Zehen
pri: 13.05.2005 (CH) No: 00848/05 classification: A61B

15.   Knochennagel für die Ferse
Pri: 27.12.2007 (CH)

16. Vorrichtung zum Einbringen eines gebogenen Nagels in einen Knochen
Pri:  18.05.2009  (CH) CH 007772009 classification A61B

Software development

–  CT/MR – Method of catching data of surfaces e.g. subchondral bone for pre-operative simulation of correcting osteotomies. Diskette available on request (Bresina/Klaue). Instruction manual “ORTHOSIM” (Klaue/Bresina).

Dissertations (Tutor)

–  M. Kowalski: “Die Knochenheilung nach Anwendung der Dynamischen Kompressionseinheit (DCU): Radiologisch-histologische Studien am Schaf”, Bern 1989

–  I. Fengels: “Knochenveränderungen nach Plattensosteosynthese im Langzeitversuch”, Basel 1995

–  K. Stoffel: “Die Belastung der Osteosynthesplatte im Verhältnis zum histologischen Bild”, Bern 1995

If it is allowed to fail, success is granted (Ernest Renan)